Screening of Hemoglobinopathies:A Validation Study of Capillary Zone Electrophoresis With HPLC

Screening of chemokine receptor CCR4 antagonists by capillary zone electrophoresis

CC chemokine receptor 4 (CCR4) is a kind of G-protein-coupled receptor, which plays a pivotal role in allergic inflammation. The interaction between 2-(2-(4-chloro-phenyl)-5-{[(naphthalen-1-ylmethyl)-carbamoyl]-methyl}-4-oxo-thiazolidin-3-yl)-N-(3-morpholin-4-yl-propyl)-acetamide (S009) and the N-terminal extracellular tail (ML40) of CCR4 has been validated to be high affinity by capillary zone...

Capillary zone electrophoresis pdf

HUMIC SUBSTANCES Capillary Zone Electrophoresis

Humic substances (HS) which are widespread in the soil, present structural complexity and polyelectrolyte properties. Many techniques and methods have been used to obtain more information about them, as reviewed by Davies and Ghabbour in 1999. The characterization of HS has been the focus of intense research for many years because the organic matter in soil contributes to the quality of the soi...

Two-dimensional capillary electrophoresis: capillary isoelectric focusing and capillary zone electrophoresis with laser-induced fluorescence detection.

CIEF and CZE are coupled with LIF detection to create an ultrasensitive 2-D separation method for proteins. In this method, two capillaries are joined through a buffer-filled interface. Separate power supplies control the potential at the injection end of the first capillary and at the interface; the detector is held at ground potential. Proteins are labeled with the fluorogenic reagent Chromeo...

Determination of Varenicline by Capillary Zone Electrophoresis

HASSAN A ALHAZMI, HAFIZ A MAKEEN, SAMI EL DEEB Department of Pharmaceutical Chemistry, College of pharmacy, Jazan University, P.O. Box 114, Jazan 45142, Saudi Arabia. Department of Clinical Pharmacy, College of pharmacy, Jazan University, P.O. Box 114, Jazan 45142, Saudi Arabia. Institute of Pharmacy, Freie Universität Berlin, Berlin, Germany Department of Pharmaceutical Chemistry, Al-Azhar Uni...